CLEAN-Contact: Enzyme Commission Number Prediction

Contrastive Learning framework for Enzyme functional ANnotation prediction combined with protein amino acid sequences and Contact maps (CLEAN-Contact) for enzyme prediction accuracy.
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AlphaFold2 Protein Structure Database

Input Uniprot ID to corresponding amino acid sequence to be processed. The result will be emailed to you once the calculation is done.

Use your own PDB

Paste in a PDB structure to be processed. The Submission ID will be used as a referece to your prediction result. The result will be emailed to you once the calculation is done.

Use an example protein structure

Submit this example amino acid sequence to get an idea of what results are returned when submitted.













If you find this tool useful in your research, please cite:

Yang, Y., Jerger, A., Feng, S., Wang, Z., Cheung, M. S., Zucker, J., & Guan, Q. (2024). CLEAN-Contact: Contrastive Learning-enabled Enzyme Functional Annotation Prediction with Structural Inference. bioRxiv, 2024-05. (Under revision at Communications Biology)

Read the study